一、 活動重點及目的：

本次活動邀請國立中央大學生醫科學與工程學系張彙音助理教授進行線上演講，分享她在利用蛋白質體學策略制定類風濕性關節炎客製化治療決策的研究成果。透過本次演講，期望能讓本校師生與同仁更進一步了解蛋白質體學在類風濕性關節炎個人化醫療的應用趨勢，激發學生對該領域的興趣與研究熱忱，並達到培育精準醫療與精準健康產業應用人才之目的。以下為講者提供之英文演講摘要。

Unpredictable treatment responses have been an obstacle for the successful management of rheumatoid arthritis. Although numerous serum proteins have been proposed, there is a lack of integrative survey to compare their relevance in predicting treatment outcomes in rheumatoid arthritis. Also, little is known about their applications in various treatment stages, such as dose modification, drug switching or withdrawal. Here we present an in-depth exploration of the potential usefulness of serum proteins in clinical decision-making and unveil the spectrum of immunopathology underlying responders to different drugs. Patients with robust autoimmunity and inflammation are more responsive to biological treatments and prone to relapse during treatment de-escalation. Moreover, the concentration changes of serum proteins at the beginning of the treatments possibly assist early recognition of treatment responders. With a better understanding of the relationship between the serum proteome and treatment responses, personalized medicine in rheumatoid arthritis will be more achievable in the near future.

二、 活動特色及執行情形：

三、 活動之質量化指標：

本次活動共有23位學生參與，其中回覆以下問題的問卷數為19。

四、 活動花絮：

主持人鄭成偉老師介紹演講人國立中央大 學張彙音助理教授。

講者張彙音老師對類風濕關節炎進行介紹。

講者解說Ｍechanism of RA。

聽眾與講者進行問答。