活動標題：「使用蛋白質體學策略制定客製化的類風濕關節炎治療決策：如何開始以及何時停止？」線上專題講座

【活動名稱】「Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop? (使用蛋白質體學策略制定客製化的類風濕關節炎治療決策：如何開始以及何時停止？)」線上專題講座

【活動日期】113年10月28日(星期一)

【活動時間】14：00～15：05

【活動地點】線上專題講座

【報名網址】點我報名

【活動對象】全校師生與高醫體系同仁

【活動目的】本次活動邀請國立中央大學生醫科學與工程學系張彙音助理教授進行線上演講，分享她在利用蛋白質體學策略制定類風濕性關節炎客製化治療決策的研究成果。透過本次演講，期望能讓本校師生與同仁更進一步了解蛋白質體學在類風濕性關節炎個人化醫療的應用趨勢，激發學生對該領域的興趣與研究熱忱，並達到培育精準醫療與精準健康產業應用人才之目的。以下為講者提供之英文演講摘要。

Unpredictable treatment responses have been an obstacle for the successful management of rheumatoid arthritis. Although numerous serum proteins have been proposed, there is a lack of integrative survey to compare their relevance in predicting treatment outcomes in rheumatoid arthritis. Also, little is known about their applications in various treatment stages, such as dose modification, drug switching or withdrawal. Here we present an in-depth exploration of the potential usefulness of serum proteins in clinical decision-making and unveil the spectrum of immunopathology underlying responders to different drugs. Patients with robust autoimmunity and inflammation are more responsive to biological treatments and prone to relapse during treatment de-escalation. Moreover, the concentration changes of serum proteins at the beginning of the treatments possibly assist early recognition of treatment responders. With a better understanding of the relationship between the serum proteome and treatment responses, personalized medicine in rheumatoid arthritis will be more achievable in the near future.

【議程】

【主講者】國立中央大學生醫科學與工程學系張彙音助理教授

【指導單位】/【主辦單位】教育部高等教育深耕計畫-教學創新精進構面-核心議題六(健康科學院)-跨域專業之健康科學實踐人才培育計畫

【執行單位】高雄醫學大學 健康科學院 人工智慧健康產業應用碩士學位學程

【協辦單位】高雄醫學大學健康科學院

【聯絡人】健康科學院 人工智慧健康產業應用碩士學位學程 鄭成偉 助理教授